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Toxoplasma IgG Specific comments
Specimen No. 8845 Clinical details:
Results
Dye test <2 IU/mL Toxoreagent <1:16 IgG ELISA negative Abbott AxSYM negative
Specific comment
No serological evidence of toxoplasma infection. Transplant from an infected donor will result in a high risk of severe or life-threatening disease associated with acquisition of organism from tissue cysts in the transplanted organ. Under such circumstances, prophylaxis should be considered urgently. Recipient is susceptible to toxoplasma infection. Patient should be advised on measures to reduce risk of acquiring toxoplasma infection while immunosuppressed.
Specimen No.
8846 Clinical details: Veterinary nurse 8-weeks pregnant. Worried about occupation risk of toxoplasma infection Results
Dye test 32 IU/mL Toxoreagent 1:64 IgG ELISA positive Abbott AxSYM positive
Specific comment Serological evidence that toxoplasma infection has occurred at some time. Absence of IgM excludes infection acquired recently. Pregnancy is not at risk from
toxoplasma.
Specimen No. 8847 Clinical details
25 year old male returned from 4-week tour of South America. Developed fatigue in last week of vacation and presented 3 days after return with lymphadenopathy. Results
Dye test <2 IU/mL Toxoreagent <1:16 IgG ELISA negative Abbott AxSYM negative
Specific comment No serological evidence of toxoplasma infection. However, seronegative findings at this time cannot unequivocally exclude acute toxoplasma infection due to very recent onset of
symptoms. A repeat sample in 2-3 weeks is required.
Specimen No. 8848 Clinical details 43 year old with 3 month history of profound fatigue Results
Dye test 30 IU/mL Toxoreagent 1:64 IgG ELISA positive Abbott AxSYM positive
Specific comment Serological evidence that toxoplasma infection has occurred at some time. Absence of IgM excludes infection acquired recently.
Specimen No. 8849 Clinical details
31 year old recently diagnosed as HIV positive. Asymptomatic and cell counts within normal range. Results
Dye test 16 IU/mL Toxoreagent 1:256 IgG ELISA positive Abbott AxSYM positive
Specific comment Serological evidence that toxoplasma infection has occurred at some time. Absence of IgM excludes infection acquired recently.
Specimen No. 8850 Clinical details
24 year old male, lymphadenopathy for 4 weeks, changes cat litter ?toxoplasmosis or glandular fever Results
Dye test 64 IU/mL Toxoreagent 1:256 IgG ELISA positive Abbott AxSYM positive
Specific comment Serological evidence that toxoplasma infection has occurred at some time. Absence of IgM excludes infection acquired recently.Toxoplasma is not implicated in this miscarriage.
Toxoplasma IgM Results Specimen No. 8851 Clinical details
Results
Dye test <2 IU/mL IgM ELISA negative IgM ISAGA negative Abbott AxSym IgM negative
Specific comments No serological evidence of toxoplasma infection. Toxoplasma is unlikely to be the cause since, although infected neonates may produce no detectable levels of antibody for up to 3
months after birth, the absence of any anti-toxoplasma IgG in this child strongly suggests the mother is also seronegative (maternal IgG would, otherwise, have been acquired passively while in utero).
Specimen No. 8852 Clinical details 49 year old male with 6 week history of lymphadenopathy and malaise. Results
Dye test <2 IU/mL IgM ELISA negative IgM ISAGA negative Abbott AxSym IgM negative
Specific comments No serological evidence of toxoplasma infection.
Specimen No.
8853 Clinical details Autologous Bone Marrow Transplant recipient. Unexplained pyrexia of unknown origin.
Results
Dye test 32 IU/mL IgM ELISA negative IgM ISAGA negative Abbott AxSym IgM negative
Specific comments
Serological evidence that toxoplasma infection has occurred at some time. Absence of IgM excludes infection acquired recently. Patient is at risk from reactivated toxoplasma infection and this can occur in the profoundly immunosuppressed with no detectable increase in IgG levels and in the absence of detectable levels of IgM. Additional testing of blood (EDTA) by PCR might be helpful in investigation of possible parasitaemia.
Specimen No.
8854 Clinical details 17 year old with acute lymphadenopathy and 5-week history of fatigue. Results
Dye test 500 IU/mL IgM ELISA positive IgM ISAGA positive Abbott AxSym IgM positive
Specific comments Serological evidence that toxoplasma infection has occurred at some time. Presence of IgM confirms infection acquired recently. These findings are consistent with acute toxoplasmosis
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