UKNEQAS Parasitology
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Toxoplasma IgG Specific comments

Specimen No.  9514

Clinical details  28 year old female, new HIV positive

Results   

    Dye test   <2 IU/mL

    Toxoreagent   <1:16

     IgG ELISA   negative

    Abbott AxSYM  negative

Specific comment No serological evidence of toxoplasma infection. Specific health education should be given to avoid infection.

 

Specimen No.  9515

Clinical details 51 year old male, lethargy and raised glands for 4 weeks.

Results  

    Dye test   <2 IU/mL

    Toxoreagent  <1:16

    IgG ELISA   negative

    Abbott AxSYM  negative 

Specific comment  No serological evidence of toxoplasma infection.

 

Specimen No.  9516

Clinical details 49 year old female ? reactivation of toxoplasmosis

 

Results 

Dye test   30 IU/mL

Toxoreagent   1:64

IgG ELISA   positive

Abbott AxSYM  positive

Specific comment  Evidence of past infection, reactivation possible. 

 

Specimen No.  9517

Clinical details 3 year old child with delayed development.

Results  

    Dye test   <2 IU/mL

    Toxoreagent  <1:16

    IgG ELISA   negative

    Abbott AxSYM  negative 

Specific comment No serological evidence of toxolasma infection

 

Specimen No. 9518

Clinical details 35 year old female ,20 weeks pregnant flu like illness for 2 weeks

Results  

Dye test   30 IU/mL

Toxoreagent   1:32

IgG ELISA   positive

Abbott AxSYM  positive

Specific comment Serological evidence of Toxoplasma infection at some time.  Further investigation is required to exclude recently acquired infection

 

Specimen No.  9519

Clinical details 12 year old boy, lymphadenopathy, drinks unpasteurised goat's milk.

Results  

Dye test   250 IU/mL

Toxoreagent   1:1024

IgG ELISA   positive

Abbott AxSYM  positive

Specific comment Results of current infection. 

Toxoplasma IgM Specific comments

 

Specimen No.  9520

Clinical details   36 year old female, 24 weeks pregnant, recent  flu like illness.

Results  

Dye test  < 8 IU/mL

IgM ELISA  negative

ISAGA M  negative

AxSym  negative

Specific comments No serological evidence of toxoplasma infection.  As symptoms are recent a second sample should be tested in 2-3 weeks to exclude current infection.

 

Specimen No.  9521

Clinical details 32 year old female, preconception check.

Results  

Dye test  < 8 IU/mL

IgM ELISA  negative

ISAGA  negative

AxSym   negative

Specific comments No serological evidence of toxoplasma infection. Patient is susceptible and health education should be given.

 

Specimen No.  9522

Clinical details 23 year old male, enlarged lymph node ?lymphoma.

Results  

Dye test  65 IU/mL

IgM ELISA  positive

ISAGA  positive

AxSym   positive

Specific comments  Serological evidence of current toxoplasma infection.

 

Specimen No.  9523

Clinical details   36 year old female, 20 weeks pregnant antenatal screen

.

Results  

Dye test  250 IU/mL

IgM ELISA  positive

ISAGA  positive

AxSym  positive

 Specific comments Serological evidence of current toxoplasma infection. Infection before conception represents little risk to the foetus so further testing (e.g. IgG avidity) should be done to determine when infection was acquired. Earlier samples should be tested if available.

 

 

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